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500 million cells. One AI. The future of cancer care just shifted.
The Cancer Research Institute just dropped something massive.
They’re partnering with 10x Genomics to analyze 20,000 cancer samples using AI, creating the most comprehensive map of immune responses to cancer we’ve ever seen.
Think about that scale: starting with 3,000 samples in the pilot, then expanding to capture data from 500 million individual cells. Each one telling us something about how the immune system fights, or fails to fight, cancer.
Here’s what makes this revolutionary:
They’re using single-cell and spatial data analysis, meaning they can see not just which immune cells are present, but exactly where they are in the tumor microenvironment. Location matters in cancer as much as it does in real estate.
The Chromium and Xenium platforms they’re using give us resolution we couldn’t dream of five years ago. We can track individual immune cells, see how they interact with cancer cells, and predict which patients will respond to immunotherapy before we even start treatment.
This isn’t just about better diagnostics. It’s about eliminating the guesswork in cancer treatment.
Right now, immunotherapy works miraculously for some patients and does nothing for others. We’ve been essentially playing roulette with $15,000-per-month treatments.
With this AI model, oncologists could know upfront: Will checkpoint inhibitors work? Should we try CAR-T instead? Or combine treatments?
The implications for community oncology are huge. Smaller cancer centers without major research infrastructure could access these AI insights, bringing precision medicine to every zip code, not just academic medical centers.
But here’s my question: As we generate 500 million data points per study, who owns this biological intelligence? The patients? The researchers? The AI companies?
We’re entering an era where your immune system’s playbook could be more valuable than your medical record.
♻️ Repost if precision oncology should reach every community cancer center
👉 Follow me, Jonathan Govette, for daily, real-time updates on healthcare technology and business news. LinkedIn Profile: https://www.linkedin.com/in/jonathangovette/
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Author:

CEO/Co-Founder @ Oatmeal Health | AI Lung Cancer Screening | Almost Became a Doctor | Engineer | Follow to Share What I’ve Learned Along the Way
I help patients get the care they need earlier, preventing late-stage cancer.
That’s been the throughline across three companies and almost 20 years in healthcare. At ReferralMD, we fixed broken referral networks so patients didn’t fall through the cracks. At Oatmeal Health, it’s lung cancer: building the diagnostic and screening infrastructure so the 85% of cases caught too late get caught early instead.
Today as CEO of Oatmeal Health, I lead a team embedding AI into radiology workflows to turn routine lung CT scans into reimbursable cancer risk assessments. We partner with FQHCs to reach underserved communities, and with health systems and payers to make early detection economically sustainable. Think HeartFlow or Cleerly, but for lungs.
Between companies, I advised at Techstars and Plug and Play, mentoring founders building in digital health. That experience shaped how I think about what separates companies that ship from companies that stall: distribution, reimbursement, and clinical trust, not just technology.
I’m a CancerX alumnus, a 3x healthcare founder, and someone who believes the biggest problems in cancer aren’t scientific. They’re operational.
We’re hiring mission-driven builders at Oatmeal Health. If you want to work on something that matters, reach out.
When I’m not working, I’m traveling, mentoring, and keeping up with one very energetic husky. 🐾
Substack – The Oatmeal Bite:
Millions of patients get less care because of who they are, where they live, or how they look. I’m fighting to change that. CEO @OatmealHealth, a startup built for the underserved. The Oatmeal Bite: intel for clinicians, investors, and advocates.
Jonathan Govette
CEO of Oatmeal Health
Substack:
https://oatmealhealthjonathangovette.substack.com/




